Ovidon, the instructions for use of which are described in the article - combined monophasic estrogen - progestin contraceptive drug intended for oral use. The drug protects the woman's body from unwanted pregnancy, stabilizes the hormone production process, helps to normalize the cycle and relieve pain during and during menstruation. The manufacturer of the product is the pharmacological company Gedeon A.O. Richter (Hungary).
Ovidon is produced in the form of a dragee of white color, on one side with a mark "ov". Prepackaged tablets in a package of 21 pieces, which are placed in paper packaging.
How does it work?
The main effect of the drug is aimed at inhibiting ovulation and preventing unplanned pregnancy.
After pre-oral use, the main components of Ovidon begin to be actively and completely absorbed in the gastrointestinal tract. In plasma, the highest saturation of ethinyl estradiol is fixed after 1.5 hours, and deogestrel - after 60 minutes. Both ingredients are metabolized in the liver. The main ingredients are mostly excreted. These components are able to penetrate the mother's milk.
Ovidon: instructions for use
The medication is taken orally on pills every day for a period of 21 days. The first reception starts from the 5th day of the beginning of the month.
The drug is better to take in the evening, in the fixed time. After completing the course, a seven-day break is recommended, during which a woman is likely to have menstruation bleeding.
The next 21-day course of treatment begins after a week break, on the same day, regardless of whether bleeding occurred during the break or not.
If Ovidon is well tolerated by the body, it is permitted to use it until pregnancy is planned.
After an abortion, the contraceptive can be taken directly on the day of medical intervention or on the second day after it.
After delivery, with the condition that the mother does not breastfeed, use the drug is allowed after 21 days. When a woman has a lactation period, it is allowed to use the remedy only 6 months after delivery. However, it must be borne in mind that the drug is released with
mother's milk also has the risk of thrombosis due to the high percentage of estrogen in its composition.
If there is an emergency situation associated with contraception, you can use 2 tablets of Ovidon in the period of 72 hours after unprotected intercourse, then, in an identical dose, 12 hours after the first use. For several days after using this medication, premature menstruation occurs, which confirms Ovidon’s contraceptive effect. It is imperative that after applying the emergency method of contraception, only barrier methods, in particular a condom, be used throughout the entire menstrual cycle.
The treatment course is prescribed individually, after a medical examination.
Actions to skip taking pills
When a pill is late for no less than 12 hours, the effect of the drug is not reduced, and the missed pill must be taken as soon as possible and continued to be used according to the usual schedule.
If the interval between use was more than 36 hours in the first or second week, in the next 2 days you need to use a couple of pills, after continuing the course and using additional methods of contraception until the end of the cycle.
In the case when the pass of the medicine was on the third week of the cycle, in addition to the measures listed above, the weekly break in taking the medicine should be abandoned and the pills should be consumed immediately from the new package.
Before use, be sure to undergo a general examination. With long-term use should be examined twice a year.
Women over 35 should use more caution.
contraceptive. This is due to the fact that the likelihood of developing thromboembolism increases after 30. The hereditary factor and bad habits, in particular smoking, affect the detection of pathology.
It is necessary to plan a pregnancy 3 months after the interruption of the reception of the drug.
The use of the drug should be urgently stopped in case of manifestation of certain ailments:
- Signs of thrombophlebitis, thromboembolism or thrombosis,
- Heart attack
- Cerebrovascular failure
- Retinal thrombosis,
- Visual impairment
- Severe chronic ailments.
Receiving Ovidon is prohibited in the event of an alleged pregnancy.
In the first months of using Ovidon, intermenstrual bleeding may occur, which gradually disappear without intervention. If bleeding recurs after previous regular cycles, you should consult a doctor to prevent the development of serious diseases.
Interactions with other medicines
The effects of Ovidon are reduced when combined with certain medications, which include:
- Antidiabetic drugs,
- Hepatic metabolism inducers,
- Remedies for seizures
- Drugs group phenobarbital,
- Wide-spectrum antibiotics,
- Hepatotoxic drugs.
The tool is not recommended for patients diagnosed with:
- Problems with the endocrine system, gall bladder, liver,
- Organic Heart Disease, Severe,
- Pathologies associated with the brain, due to painful transformations of cerebral vessels in combination with poor circulation,
- Arterial hypertension,
- Sickle - cell and / or chronic hemolytic anemia,
- Propensity for thrombosis,
- Seizures due to calcium deficiency in the body,
- Malignant tumors,
- Excessive sensitivity to drug components.
The drug can not be used also during pregnancy and lactation.
Ovidon's replacement agents are:
The cost of the drug Ovidon on average ranges from 350 - 500 rubles on average.
Features of the flow of menstruation when using Ovidon
In the first months of using Ovidon, like all other contraceptives, a failure or movement of the menstrual cycle is recorded. Monthly after such pills may be delayed.
Due to the characteristics of the body, periods during the use of contraceptives can be shifted for different periods. The normal reaction of the body, if there are no monthly periods about 4 days after the end of the Ovidion administration phase. If the delay is more than 7 days, you need to consult a doctor.
Two months after the start of the use of Ovidon, the body is rebuilt, all problematic phenomena disappear.
Estrogen-progestin, contraceptive. The impact principle is based on the ability of the active components to inhibit ovulation, affect the normal course of the secretory phase of the menstrual cycle, causing the development of temporary atrophic changes in endometrium and obstructing the implantation of a fertilized egg. Ovaries while taking contraceptives are in the resting stage. Additionally, changes occur in the fallopian tubes, cervical canal, endometrium. Increased viscosity of secretions from the cervical canal prevents sperm from entering, and thinned endometrium does not allow the egg to attach to the uterus. Such a complex effect excludes fertilization. The effectiveness of the drug reaches 100% when properly applied. Ovidon Richter is a combined, high-dose, hormonal drug.
Pharmacodynamics and pharmacokinetics
The active ingredients are absorbed in the small intestine quickly and efficiently. Associated with plasma proteins by 94%. The active ingredients are evenly distributed throughout the organs and tissues. The maximum (max) concentration is recorded after 2 hours. Most ethinyl estradiol accumulates in adipose tissue. During the day, the medication is excreted by the kidneys and the hepatic system.
Indications for use
- functional disorders of the menstrual cycle,
- acyclic masterbatch bleeding,
- pain syndrome in the middle of the menstrual cycle (ovular pain syndrome).
- body weight fluctuations
- dyspeptic changes
- cramps in the calf muscles,
- bleeding from the vagina,
- reduced glucose tolerance,
- rashes on the skin,
- increased fatigue
- mood lability
- libido change.
Ovidon, instructions for use (method and dosage)
As a contraceptive, Ovidon Richter takes one pill of 21 days daily, starting from the 5th day of menstruation. The preferred time of admission - in the evening, after meals. After taking the 21st pill, they take a week-long break during which they appear menstrual bleeding. The next course begins immediately after the completion of the weekly break (even if there was no bleeding during this period).
When smoking increases the risk of complications of the vascular system and the heart (in the risk group women over 35 years). Before starting treatment, as well as with a long reception, it is necessary to be monitored by a gynecologist. Treatment is stopped when registering the following negative symptoms:
- swollen veins
- migraine-like headaches,
- unusual pain in the legs,
- chest pain when coughing, breathing,
- movement disorders
- changes in hearing, visual perception.
6 weeks before the planned surgery, Ovidon is being canceled. At high blood pressure the risk of thrombosis increases significantly. When appearing porphyriaswith frequent attacks epilepsy, cholestasis, itch, jaundice and hepatitis treatment is stopped. Glucose tolerance changes when taking Ovidon in parallel with anti-diabetic therapy. Liquid stools, vomiting contribute to the removal of the medication taken from the body, which may adversely affect contraception, which requires the use of other methods to prevent pregnancy.
The drug is considered an effective and reliable contraceptive that is easy to use. The experience of using the drug indicates its therapeutic effect in dysfunctional uterine bleeding, menstrual pain, dysmenorrhea. Practical experience and medical sources indicate the protective effect of the drug. Proved that long-term therapy reduces the risk of oncopathology from the reproductive system. It is noted that the intake of contraceptives allows you to fight with iron deficiency anemia. Among the drawbacks of the medication is a high risk of thrombosis, which is typical for all contraceptives. The drug is well tolerated by patients, available at a cost.
Dosage and administration
Inside, for the purpose of contraception - in the evening 1 tab. per day, starting from 1–5 days of menstruation, for 21 days. After a 7-day break (during which menstrual bleeding begins), proceed to the next 21-day course. For therapeutic purposes, the dose and treatment regimen are selected individually.
Reception should be stopped in the event of pregnancy, thrombosis, thromboembolism or thrombophlebitis, cerebrovascular disorders, myocardial infarction, retinal thrombosis, deterioration of visual acuity, exophthalmos, diplopia, repeated persistent headaches, in the event of any severe chronic disease, Special attention is required when appointing women over 35 years old.
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Opinion "Doctors of the Russian Federation" on the drug Ovidon
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Instructions for use of Ovidon
According to the instructions, Ovidon is prescribed to take orally. Once a day from 1-5 days of the menstrual cycle and over the next 20 days. Then you should take a break in reception for 7 days. According to the doctor's prescription, the drug in the form of dragees, in the amount of 28 pcs., Can be taken continuously throughout the entire course of treatment.
For taking Ovidon, you must select a specific time (breakfast or dinner) to constantly maintain the concentration of hormones in the blood for effective contraception.
The attending physician must control the patient's Ovidon's menstrual cycle, since the drug may shorten or increase the duration of the cycle, as well as possible vaginal bleeding of varying intensity.
Ovidon received good reviews as a long-acting contraceptive drug that ensures hormonal stability and regularity of the menstrual cycle.
In accordance with the instructions of Ovidon, during the period of interruption in his admission, other non-hormonal contraceptives should be taken, the individual dosage of which should be determined by the attending physician.
Dosing and Administration
To prevent pregnancy, take 1 tablet of Ovidon daily in the evening. Reception should begin with 1-5 days of menstruation. After taking 21 pills (full pack), you should take a 7-day break. At this time, menstrual bleeding should occur.
For therapeutic purposes, the doctor selects the dosage and regimen of the drug individually.
Composition and release form
Ovidon dosage form - tablets: white, on one side with the engraving “ov” (21 pieces in a blister pack, in a cardboard box 1 pack).
Ingredients 1 tablet:
- Levonorgestrel - 0.25 mg,
- Ethinyl estradiol - 0.05 mg.
Clinico-pharmacological group: progestin contraceptive drug.
What does Ovidon help?
Used as a contraceptive.
Also, to eliminate a number of gynecological symptoms associated with the cycle, such as premenstrual tension, dysmenorrhea (menstrual disorder), polymenorrhea (menstrual disorder characterized by prolonged (more than 6 days) and abundant menstruation), pain in the middle of the cycle, etc. .
Pharmacy sales terms
The drug is available on prescription.
In summary, what can I say about the use of Ovidon tablets with a duration of six months:
1) term of use: 6 months (28 days each)
2) the price was very democratic then 40 rubles.
3) nature of menstruation: the number of days increased from 4 to 6, but the number of menses per day did not increase
4) hair, nails: without negative changes, did not break and did not fall down
5) face: acne, rash not followed
6) intermediate bleeding: none
7) weight: stably 60-61 kg (I was not “spread out” and I did not lose weight)
8) emotional background: became a bit more aggressive
9) the breasts were filled like two weeks from the 4 weeks of the cycle (I think this is a large dose of hormones, later I remembered this feeling when I got pregnant)
I recommend these pills, especially as a means of establishing the menstrual cycle. Monthly - at the same time, on the same day come, every 28th day! I, however, never had any gaps in the cycle before applying the preparation, but it “sailed” and was 26-32 days.
Ovidon: instructions for use
Combined oral contraceptives occupy a leading place in the field of contraception among other contraceptives.
Who do they suit first? Of course, disciplined women and girls who appreciate high reliability, and also want to get therapeutic effects from the use of funds.
For contraception, Ovidon is taken according to the basic classical scheme. It is often called "21 + 7".The drug is taken daily in the amount of one tablet. The period of taking the pills is 21 days. Then the reception is stopped for 7 days. In the days of a break, a woman usually has a menstrual period, which may be slightly different from normal. Spotting are scanty, smearing. On the eighth day, you are required to start taking the pills again. Pay attention - it is necessary to begin tablets from new packing.
For convenience, the package has an arrow and a number.
Reception courses can be long. If a woman feels well while taking Ovidon, then there is no need to change it for another drug, or to take a break from taking it. On the contrary, Ovidon should be taken for a long time until the woman has planned a pregnancy. No “once a year” breaks are recommended. Scientists have shown that taking breaks increases the risk of various side effects with the newly resumed taking of the drug.
Long-term use of the drug helps to preserve the health of a woman. If a woman does not violate the rules for taking Ovidon, then his contraceptive effect persists for seven days of rest.
The use of Ovidon, as with all hormonal oral contraceptives, can cause adverse effects. Most often they occur at the beginning of the pill. The fact is that the body can not immediately adapt to the amount of hormones that are introduced during the use of the drug. After several months of taking the remedy, the negative phenomena disappear.
Estrogen, which is part of the drug, can cause symptoms of "false pregnancy":
- vaginal discharge,
- hypersensitivity and engorgement of the mammary glands.
The progestogens that make up the product cause the following side effects:
- vaginal dryness
- acne on the face,
- decreased libido
- weight gain due to fluid retention.
Allergic reactions sometimes occur when taking Ovidon. In this case, you must immediately cancel the drug.
Quite often, when you receive intermenstrual bleeding occurs, less often there is some discomfort when wearing contact lenses.
Side effects when taking the drug, as a rule, are intermittent, often go away on their own within 2-3 months from the start of use.
Receiving Ovidon for a long time can cause the appearance of dark pigment spots (similar are during pregnancy). Changes in biochemical parameters in the blood test may appear: an increase in sugar levels, blood pressure indicators, exacerbation of liver and gallbladder diseases, and development of thrombophlebitis. Characterized by changes in the skin: the appearance of acne, dry skin and hair, hair loss. In rare cases, taking Ovidon causes mycosis of the vagina, candidiasis.
The likelihood of side effects increases when using the drug without a doctor's prescription.
Probability of thromboembolism
For the appointment of Ovidon, a woman’s life history is carefully studied, the presence of thromboembolism and thrombosis, changes in blood clotting are taken into account. If they are even in family history, the use of Ovidon is unacceptable.
With prolonged use of funds may develop terrible complications of thrombosis. The likelihood of thromboembolism may increase, depending on the age of the woman, and such a sign as smoking. Therefore, women taking the drug over 30 years old must quit smoking.
Risk of developing malignant tumors
Experts have proved that with the regular use of sex hormones for more than eight years, the development of benign liver tumors is observed in rare cases, and the malignant neoplasms of this organ are extremely rare.
With the increase in pain in the upper abdomen while taking Ovidon there is a suspicion of a liver tumor. In this case, the drug is stopped until the causes of the pain are determined. If a hepatic impairment is detected to some extent, the woman should be seen by the therapist every three months. For this period, the drug is stopped until the cause of the violations is ascertained.
In the case of vomiting or diarrhea, Ovidon's administration is recommended to continue, but an additional method of contraception should be used.
Particular attention is drawn to the feasibility of receiving funds for diseases of the endocrine, cardiovascular and digestive systems. The presence of pathologies such as diabetes mellitus, kidney disease, thrombophlebitis, hypertension, multiple sclerosis, mental illness with symptoms of depression, and bronchial asthma require special monitoring of the woman’s health status.
During the administration of Ovidon, medical monitoring is required at least every 6 months.
After suffering viral hepatitis, it is allowed to use the drug no earlier than 6 months after the normalization of liver functions.
Comparative characteristics of Ovidon and its analogues
All of these drugs belong to the combined oral contraceptives, as part of have two hormones - levonorgestrel and ethinyl estradiol, in the dosage of which there are slight differences.
By the action of all the above drugs are divided into:
1. Monophasic - Rigavidon, Mikroginon and Miniziston.
2. Biphasic - Anteovin.
3. Three-phase - Triziston.
Three-phase drugs were created to reduce the total dose of hormones during the course. But then low-dose monophasic drugs appeared, and there was no need to use three-phase drugs. Biphasic and three phase birth control pills to a greater degree imitate the menstrual cycle, but at the same time, have low efficiency. High-dose monophasic drugs are effective with proper regular intake of 100%.
Therefore, three-phase contraceptives are more indicated for the treatment of ovarian dysfunction, for the establishment of the menstrual cycle and the treatment of premenstrual syndrome. For effective contraception, monophasic high-dose drugs are preferred, to which Ovidon belongs.
Using the drug as the "next day's pills"
Emergency contraception is a way to prevent pregnancy immediately after unprotected intercourse.
For this method, proposed in the seventies of the 20th century by Albert Yuzpe, certain drugs are suitable, including Ovidon. Immediately after unprotected sexual intercourse, a woman must drink 2 tablets of Ovidon within 72 hours, and after 12 hours, repeat the same dose.
The method is remarkable in that it can be used for emergency contraception any combination drug containing levonorgestrel in its composition in a dose of 0.5 mg. The dose per dose should be 1 mg. Therefore, such means as Regividon, Silest, Marvelon are suitable for this method - 4 tablets in two doses.
Within a few days after taking the pills, premature menstruation begins, which indicates the contraceptive effect of the method.
It is important to remember that the method of emergency contraception is less reliable and harmless than regular contraception. It should be used only in emergency cases.
Ovidon is used not only to prevent unwanted pregnancies, but also for medicinal purposes.
So, in case of painful menstruation (dysmenorrhea), along with drugs of other groups, treatment with high-dose combination drugs, primarily Ovidon, is widely used. The prescribed complex treatment helps relieve pain.
In ovarian forms of amenorrhea, cyclic hormone replacement therapy is performed.
The use of the following synthetic progestins is possible during cyclic hormone therapy: Non-Ovlon, Ovidon, Rigevidon. Drugs prescribed in the period from 5 to 25 day cycle, take 1 tablet per day.
It is advisable to use the drug for menopausal syndrome, which is caused by a lack of ovarian function. Ovidon or Rigevidon tablet is divided into 6-8 parts, and take one by one. Duration of use - 15-25 days.
Juvenile bleeding often occurs between the ages of 14-18. Conservative treatment includes the use of hormonal agents. Estrogen-progestin drugs - Non-Ovlon, Bisecurin, Ovidon - prescribe 4-5 tablets per day, until complete bleeding stops. In consequence, the dose is reduced. The duration of treatment is 15-18 days.
In the treatment of dysfunctional uterine bleeding in the reproductive period, hormonal contraceptives are used, including Ovidon.
Contraceptive pills Ovidon - reviews
Reviews of most women taking the drug Ovidon, have a positive color, but there are also negative opinions. To achieve positive effects, it is important to take the drug regularly and for a long time.
Pros when taking Ovidon:
- high reliability, good portability, good reversibility,
- simplicity and availability in application,
- eliminating the pain of menstruation,
- recovery of the menstrual cycle
- recovery of libido
- improving mood, reducing irritability in the premenstrual period,
- the effectiveness of the treatment of dysfunctional bleeding,
- reducing the risk of malignant neoplasm of the female reproductive system and internal organs,
- reduction of acne, skin rashes and acne,
- reducing the number of female genital inflammatory diseases,
- therapeutic effect in hyperandrogenic conditions, slowing the growth of unwanted facial hair,
- therapeutic effect in case of iron deficiency anemia.
In our country in recent years there has been a tendency towards the widespread use of combined oral contraceptives. For many women, this is the method of choice. Without a doubt, the main advantages of all hormonal birth control pills are reliability, effectiveness, ease of use.
The experience of using Ovidon testifies to the therapeutic effect in dysmenorrhea, pain during menstruation, dysfunctional uterine bleeding. Medical sources and practical experience indicate the protective effect of the drug. With prolonged regular use of Ovidon may reduce the risk of developing cancer of the female genital. Women who use Ovidon, get rid of iron deficiency anemia.
Of course, one cannot oppose one means to another. But for Ovidon, one can find use in a large category of women, depending on age, activity in sexual life, taking into account side effects, indications and contraindications. There can be no perfect contraceptive for everyone. But with proper use, Ovidon is recommended to be used safely by many women. It is important to remember that only a specialist selects a contraceptive. A woman, trusting a doctor and taking contraceptives, protects herself from unwanted pregnancy.
The average price of the drug in pharmacies is 300-400 rubles. per pack.
OK "Ovidon", as stated in the instructions for use, includes synthetic hormones gestagen and estrogen, under the action of which ovulation ceases, and the ovaries are immersed in a stage of rest. Simultaneously with this process, metamorphosis is observed in the mucous membrane of the cervical canal, in the endometrium and fallopian tubes.
Secretions in the cervical canal become more viscous, and this prevents the progress of sperm, and the endometrium becomes so thin that it does not allow the egg to implant in the uterus. Such transformations in the female body exclude the possibility of fertilization and with the right reception of OK, its effectiveness is almost 100%.
The active ingredients of the drug (ethinyl estradiol and levonorgestrel) are absorbed very soon in the small intestine. Indicators of the level of binding to plasma proteins are about 94%. Already after 2 h there is a limiting concentration of substances in the blood that penetrate into different tissues and organs. As a rule, ethinyl estradiol accumulates in body fat. About 10% of hormones are able to penetrate into breast milk, so during lactation, OK should be canceled. The withdrawal of the drug is carried out within 24 hours, through the liver and kidneys.
During pregnancy and lactation
Pregnancy is a contraindication to the reception of funds, therefore, when confirmed, it is necessary to cancel OK. Also, do not forget that hormones are in breast milk, and this can cause complications in the development of organs and systems of the infant, so that during the feeding period the drug should also be canceled.
As for abortions, after them it is recommended to start taking OK immediately on the day of surgery, or a maximum of the following day. After childbirth, it is possible to use the drug on day 21 (when the woman is not breastfeeding) or for 7 months from the day of birth, if lactation is practiced. However, it is preliminary recommended to consult with your doctor about the appropriateness of receiving OK, since it may lead to the development of thrombosis and thromboembolism in the postnatal period.
There is a decrease in the effectiveness of the contraceptive with parallel use with drugs such as:
- Hepatotoxic drugs
- Phenobarbital Derivatives
- Antidiabetic drugs
- Anticonvulsant Medicines
- Inductors of hepatic metabolism
- Broad-spectrum antibacterial agents.
Term and storage conditions
The drug belongs to the List B, which means that it should be stored at a temperature of 15-30 degrees, in a dry place. Ovidon's shelf life is 5 years.
The most common analogues of the drug "Ovidon" can be called such OK as "Rigevidon" and "Mikroginon." It is also a monophasic combined hormonal contraceptive.
Manufacturer: Gedeon Richter, Hungary
Cost: 495-620 rubles
- Reduces the risk of gynecological ailments with regular use
- It has a small number of contraindications.
- Virtually no side effects.
- Slight therapeutic effect
- May inhibit milk production during lactation.
- In the case of alcohol consumption, the contraceptive effect of the drug is reduced.
Manufacturer: Bayer Pharma AG, Germany
Price: 160-220 rubles
- Is the prevention of tumors, inflammation of the pelvic organs and ectopic pregnancy
- It has several forms of release.
- A large number of contraindications and side effects
- Relatively long recovery period after long-term use.
- When overdose provokes vomiting, nausea or vaginal bleeding (no antidote).
The effectiveness of Ovidone decreases with combined use with such drugs as pyrazolone derivatives, sulfonamides, inducers of microsomal oxidation (including barbiturates, rifampicin, phenytoin), tetracyclines.
Ovidon's analogues are: Rigavidon, Miniziston, Anteovin, Trinordiol, Miranova, Triziston, Mikroginon, Gravistat.
The price of Ovidon in pharmacies
The price of Ovidon averaged 300–400 rubles (for a package of 21 pieces), but at the moment the drug is not available in pharmacies.
Education: First Moscow State Medical University named after I.М. Sechenov, specialty "General Medicine".
Information about the drug is generalized, is provided for informational purposes and does not replace the official instructions. Self-treatment is dangerous to health!
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Ovidon oral tablets (Ovidon)
Instructions for medical use of the drug
- Indications for use
- Release form
- Pharmacodynamics of the drug
- Side effects
- Dosage and administration
- Interactions with other drugs
- Admission precautions
- Special instructions for admission
- Storage conditions
- Shelf life